Lofnac Rectal Suppositories are for the relief of headaches, toothaches, menstrual pain, sprains and strains, soft tissue injuries and athletic injuries. They also relieve pain, ease inflammation and reduce the swelling in conditions affecting the joints, muscles and tendons including rheumatoid arthritis, osteoarthritis, acute gout, and ankylosing spondylitis. It contains Diclofenac Sodium, a non-steroidal anti-inflammatory drug (NSAID) as the active ingredient.